Would you take a “Migraine Vaccine”

Let’s think about this: Emgality/Ajovy/Aimovig are monoclonal antibodies to the CGRP ligand and receptor respectively. Nothing stops us from creating an immunizing antigen that teaches the body to create IGG against the CGRP ligand or Receptor which I turn will provide you with your own version of the monoclonal ABs.

This comes with implications: what’s done cannot be undone, what would happen during pregnancy, will there be side effects decades down the line etc.

Having said that, the vaccine is in animal trials.