Commute to hybrid work

Hi, I received a hybrid job offer from Berlin, which is 90 minutes by train or car in one direction. I'm wondering if commuting 2 or 3 times a week is worth it in the long run. Financially, I'm counting on living in the LCOL area, where I currently live, to save around €1200-1500€ per month compared to Berlin. Besides, Berlin itself seems too big a city for me to live in.

Does anyone commute like that? Do you think it makes sense to plan a career in Berlin in such a hybrid work arrangement? Even leaving aside this job offer, but in the future I only have one employer in my city, so somehow I would have to manage work in Berlin, which is the nearest larger metropolis with a broad job market.

EDIT: I forget to add: I have a direct train connection every hour and a very good Autobahn route for the car