Have U.S. Presidents ever been able to successfully prevent Colonization efforts?

Due to a certain Musical Artist’s recent release, my curiosity was piqued on the history of the Annexation of Hawaii. Having read through related Wikipedia articles, it is my understanding that president Grover Cleveland was an advocate for Hawaii’s sovereignty. His efforts of reinstating Lili’uokalani were however largely ineffective.

I am not very familiar with the inner workings of the US government at the time, but my understanding of said wikipedia articles would indicate that financial interests of the non-native Hawaiian residents played a large role in the Overthrow and the lack of action on the senate’s behalf.

A lot of things stand out to me as unique about the situation, but none as much Cleveland’s active involvement against the U.S. expansionism. Yet he was not successful in these efforts.

My question, considering the ample history of U.S. foreign involvement, is if there have been individuals who like Cleveland, sought to prevent annexation of territories that would serve U.S. economic interest but were in contrast successful? Have there been failed attempts at similar land acquisitions or other invasions?

I welcome any corrections if I misunderstood the Hawaii Annexation. Or anything to enrich my understanding of the subject :)

TL;DR: Has a US president/historic figure ever successfully help prevent the U.S. from overthrowing a foreign government?